In this interview Tadeus Reichstein discusses his long and distinguished career as an organic chemist. He begins by recalling his family and early education in Germany and Switzerland. The interview continues with Reichstein describing his advanced work at the Swiss Federal Institute of Technology (ETH) and recalling his professors and colleagues, especially Staudinger and Ruzicka. In 1938, Reichstein moved to the Pharmaceutical Institute at Basel, and the central portion of the interview focuses on his research leading to the Nobel Prize in 1950. This includes work in Vitamin C synthesis, cortisone and other adrenal hormones, and glycosides. The interview concludes with Reichstein expressing his personal philosophy, his views on the changes in chemistry, and his interest in botany.