Paul Weisz begins his oral history interview by discussing his family background in Austria-Hungary after World War I period, when his family moved to Berlin. Weisz was educated in the Gymnasium, where he developed an interest in physics and chemistry. Weisz attended the Technical University in Berlin and spent his free time in the laboratory of Wolfgang Kohlhoerster at the Institute of Cosmic Radiation Research, where he worked on Geiger counter instrumentation and cosmic ray measurements. Because of Hitler's rise to power, Weisz arranged an exchange program with Auburn University, earning his B.S. in physics in 1940. At the Bartol Research Foundation in Pennsylvania, Weisz worked on radiation counting and projects relating to the National Research Defense Council. After gaining clearance to do classified work, he moved to the MIT Radiation Laboratory where he helped to develop a long range navigation trainer (Loran). He accepted a position with Mobil Corporation, where he worked on catalysis. In 1966, he completed his Sc.D. at the Eidgenössische Technische Hochschule in Zurich, where he had worked with Heinrich Zollinger on dye chemistry. Weisz concludes the interview by discussing innovation in industry, the importance of interdisciplinary thinking, and his later work on Alzheimer's Disease and angiogenesis.