In this interview Dr. Fuller traces his early years and the development of his interests in radio and in chemistry. Encouraged by an outstanding high school teacher, Fuller won a scholarship to the University of Chicago. Economic pressures forced him to break studies for periods of employment in the analytical laboratories of the General Chemical Company and as a photoengraver at the Chicago Tribune, but Fuller persists and completes his doctorate under W. D. Harkins. Dr. Fuller enlivens the interview with recollections of Harkins and Julius Stieglitz. Appointment as a research chemist under R.R. Williams at Bell Laboratories introduces Calvin Fuller to the infant science of synthetic polymers and to xray crystallography. World War II sees Fuller in Washington, D.C., heading polymer chemistry research as part of the synthetic rubber program. On return to Bell Laboratories after the war, Fuller decides to move to solid state chemistry and describes his work on semiconductors, leading to the development of the photovoltaic cell.