An Oral history with Isabella and Jerome Karle

An Oral history with Isabella and Jerome Karle

  • 1987-Feb-26 (First session)
  • 1987-Jun-15 (Second session)
  • 1987-Sep-09 (Third session)

Isabella and Jerome Karle met while both were pursuing doctorates in physical chemistry under Professor Lawrence Brockway at the University of Michigan. After earning their degrees (and marrying), they worked on the Manhattan Project at the University of Chicago’s Metallurgical Laboratory. After a brief return to the University of Michigan, the Karle’s moved to the United States Naval Research Laboratory, where they focused on the development of X-ray crystallography. They worked together to develop a direct method for determining crystal structures, work for which Jerome Karle, with their colleague Herbert Hauptman, was awarded the Nobel Prize in Chemistry in 1985. Over the course of three interview sessions, the Karles discuss their childhoods, early education, undergraduate and graduate work, careers and collaborations.

Place of interview
Original file type PDF, MP3
  • 94 pages
Rights In Copyright - Non-Commercial Use Permitted
Rights holder
  • Science History Institute
Related URL
Credit line
  • Courtesy of Science History Institute

Physical location


Cite as

Jerome Karle, interviewed by James J. Bohning in Naval Research Laboratory (U.S.) on September 9, 1987. Philadelphia: Science History Institute, n.d. Oral History Transcript 0066.

  Export citation (RIS) ?

This citation is automatically generated and may contain errors.

Transcript (Published Version)

The published version of the transcript may diverge from the interview audio due to edits to the transcript made by staff of the Center for Oral History, often at the request of the interviewee, during the transcript review process.

Complete Interview Audio File Web-quality download

14 Separate Interview Segments Archival-quality downloads