Cheves Walling begins this interview by describing his family, early education, and undergraduate days at Harvard. He then discusses his graduate education at the University of Chicago, stressing the major review article on the peroxide effect that he and Frank Mayo wrote in 1940. Walling next examines the research that he undertook at Du Pont, U.S. Rubber, and Lever Brothers, emphasizing the work that he did before 1950 at U.S. Rubber. Finally, Walling examines his academic career at Columbia and the University of Utah. Throughout the interview he reflects upon the emergence and maturation of physical organic chemistry.