Glen A. Evans grew up in San Diego, California, the oldest of three children. He first decided on a science career when he was in high school, and during the summer before he matriculated at UCSD he worked in Renato Dulbecco’s lab. He graduated in just three years, with a major in biology, enough credits for another major in chemistry, and with two published papers. Evans entered the Medical Scientist Training Program offered by the National Institutes of Health (NIH), choosing UCSD, where he continued work he had begun as an undergraduate in Michael G. Rosenfeld’s lab on activation of hormone genes in the pituitary gland. Evans’ first job was in Philip Leder’s lab at the NIH’s Public Health Service, funded by the U.S. Navy. Finding the lab too large, Evans moved to Jonathan Seidman’s lab to work on histocompatibility antigens. When Leder and Seidman left NIH for Harvard University, taking most of the lab with them, Evans decided to finish his third year and then move to the Salk Institute for Biological Studies. Though he has to fund his own work at the Salk he finds it intellectually free, smaller, and more efficient. His lab is mostly involved with the Human Genome Project. To finish the interview Evans discusses his documentation, a typical day at work, his rolling contract, and his ideal lab environment.