Frank R. Nissel begins the interview by describing his early childhood and schooling in Berlin, Germany, and subsequent move to Egypt due to the emergence of Adolf Hitler's policies. Arriving in Egypt at the age of seven, Nissel continued his multi-lingual education. After a six-month escape to Jerusalem until the end of World War II, Nissel returned to Egypt to attend the American University at Cairo. He continued his education in the United States, studying chemical engineering at the Virginia Polytechnic Institute.

He began a successful decade of work with Union Carbide Corporation after earning his M.S. in 1946, finally leaving to become co-founder of Prodex Corporation with Albert Kaufman. At Union Carbide, Nissel focused on vinyl calendaring, but returned to his more mechanical instincts by building extruders in his new business venture. The machinery built at Prodex revolutionized plastics machinery by being more efficient, yet less expensive, than its competitors, making waves with companies like Dow Chemical Company. Nissel continued to improve his products, while ensuring customers a good value. In 1955, Prodex was sold to Koehring Company, and after a brief time of consulting, Nissel joined forces with Welding Engineers Company to form Welex Corporation. At seventy-six years old, Nissel is not ready to retire, but has confidence that when that time comes, the company he founded will be well taken care of. For his innovation and contributions to the plastics industry Nissel has earned many honors and awards, including membership in the Plastics Hall of Fame. Nissel concludes the interview by sharing a bit about his family today, as well as interests outside of the work sphere, especially the jazz music scene.