The interview begins as Harold Eugene Thayer recalls his family background and growing up in Rochester, New York, during the early Depression. He remembers the strong influence of his mother and his decision to attend MIT, where he pursued a course combining chemical engineering and business administration. As the interview continues, Thayer describes his first job, training in sales at American Cyanamid and his decision to leave for a position with Mallinckrodt Chemical Works. At Mallinckrodt, Thayer became involved in work for the War Production Board and then the Manhattan District, where he managed much of the company's uranium processing. The central portion of the interview focuses on Thayer's long-standing outspokenness in management discussions, his relationship with Edward Mallinckrodt, Jr. , and his rise through management to presidency of the company. As president, Thayer was responsible for Mallinckrodt's strong growth, accomplished primarily by structural reorganization, developing the company's niche in the diagnostic products market, and making key successful acquisitions. While the interview highlights Thayer's views on the importance of teamwork, selflessness, and integrity throughout the company's work, it also examines some management mistakes and problems over the years. Concluding comments describe Thayer's community affairs work, his views of government regulation and chemical innovation, and his pride in receiving the Society of Chemical Industry Medal.