Letter from Paul Ehrlich to Georg Bredig
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Paul Ehrlich (1854 – 1915), a German physician and scientist, thanks Georg Bredig (1868-1944) for sending him a scientific paper and mentions that he will send Bredig some of his recent scientific publications dealing with experiments in immunochemistry, particularly diptheria. Paul Ehrlich won the Nobel Prize for Physiology or Medicine in 1908. His most significant achievements include finding a cure for syphilis in 1909 and developing the technique that led to Gram staining bacteria and distinguishing between different types of blood cells.
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Ehrlich, Paul. “Letter from Paul Ehrlich to Georg Bredig,” n.d. Papers of Georg and Max Bredig, Box 1, Folder 35. Science History Institute. Philadelphia. https://digital.sciencehistory.org/works/nt69rwb.
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GEH. MED. RATH. PROF. DR. P. EHRLICH
WESTENDSTRASSE 62
Hochverehrter Herr.
Ich muß um entschuldigung bitten, daß ich die liebens würdige übersendung Ihrer wichtigen u[nd] mich besonders interessierenden arbeit noch nicht mit einem dank beantwortet habe. Ich hatte aber die letzten wochen zu vielerlei abhaltungen.
Ich gestatte mir Ihnen einige meiner letzten separata einzu senden, aus denen Sie vielleicht entnehmen werden, daß auch ich mich bemüht habe in dem so dunkelen immunitätsgebiet exakt und entsprechend den modernen chemischen anschauungen
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(page 2)
entsprechend zu arbeiten. Der ausgangspunkt meiner betrachtungen ist die thatsache, die ich für diphtherie gift dicker aerostatisch u[nd] die seither von Madsen an dem gleichen objekt bestätigt hat, daß bei längerem stehen von giftbacillen das sättigungsvermögen für antikörper constant bleibt, während sich die in dieser menge enthaltenen dates-daten erheblich (auf die hälfte u[nd] mehr) vermindern.
Wenn ich einmal nach Leipzig komme, werde ich mir erlauben Sie aufzusuchen.
Mit besten empfehlungen, u[nd] in vorzüglicher hochachtung
Ihr sehr getreuer
P. Ehrlich.
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PRIVY MEDICAL COUNCIL, PROFESSOR DR. P. EHRLICH
WESTENDSTRASSE 62
Dear Sir,
I must apologize for not yet replying with a thank you note for graciously sending me your important work, which is of particular interest to me. However, I've received too many treatises in the last few weeks.
I am taking the liberty of sending you some of my latest offprints, from which you may infer that I have also attempted to work precisely and in accordance with modern views of chemistry in this obscure area of immunity.
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The point of departure for my theoretical considerations is the fact that if poisonous bacilli are left standing for a long time, the saturation capacity for antibodies remains constant, while the bacilli contained in this amount of data are reduced considerably (by half and more). I consider diphtheria poison to be more aerostatic, which has since been confirmed by Madsen with the same substance.
If I ever come to Leipzig, I will take the liberty of visiting you.
With best wishes, and the utmost respect
Your very faithful,
P. Ehrlich
