Marion David Francis begins his interview with a discussion of his childhood in Canada. Deeply influenced by his industrious parents and siblings, Francis worked his way through high school and college at a logging camp. He received his B.A. in chemistry in 1946 and his M.A. in chemistry in 1949, both from the University of British Columbia. Francis married shortly after, and he and his wife moved to Iowa, where he continued his studies at the University of Iowa, obtaining a Ph.D. in biochemistry in 1953.
Francis accepted a position with Procter & Gamble in 1952. His first work there involved research on detergents and skin penetration. Procter & Gamble then moved Francis into hair research. Finally, Francis moved to the dental section, where he became involved with fluoride research. Using both human and bovine dental samples, Francis explored enamel resistance to calcium fluoride. He also proved in other lab tests on rats that fluoride had an anti-enzymatic effect on teeth, and that fluoride treatments helped protect rats' teeth from decay. Francis continued to do dental research on calculus and its safe removal from teeth without damaging the enamel. Speaking on scientific innovation, Francis touches on team effort and support, as well as management and research and development. Francis concludes the interview with a reflection on winning his scientific awards and final thoughts on his family.