James A. Fisher begins the interview with a description of his family and early years in Pittsburgh, Pennsylvania. After graduating early from Yale University because of the bombing of Pearl Harbor, Fisher secured a position in a smelter plant making aluminum for warplanes at Alcoa Inc. In 1945, Fisher left Alcoa to work for his father, Chester G. Fisher, at the family business, Fisher Scientific International Inc. While at Fisher Scientific, Fisher became fascinated with his father's collection of alchemical art. Fisher's interest grew to the extent that he began to purchase paintings, engravings, and photographs relating to alchemy to add to the growing Fisher Collection. After the death of his father, Fisher was instrumental in the creation of the Fisher Museum, which was used to display the Fisher Collection, and the Pasteur Room, which was dedicated to the achievements of Louis Pasteur. Fisher concludes the interview with reflections on his role in the donation of the Fisher Collection to the Chemical Heritage Foundation.