Oral history interview with David W. Golde

Oral history interview with David W. Golde

  • 1999-Dec-15

David Golde begins the interview with a discussion of his early years and education in Bayonne, New Jersey. In high school, Golde developed an interest in medicine, which was stimulated by his biology teacher. He received his B. S. in chemistry from Fairleigh Dickinson University in 1962. He then attended medical school at McGill University, graduating in 1966. After graduation, Golde completed his internship under the supervision of Dr. Holly [Lloyd] Smith at the University of California, San Francisco [UCSF]. Golde joined the faculty at UCSF after completing his residency at the National Institutes of Health. His experience in clinical pathology at NIH steered him into hematologic research at UCSF in Martin J. Cline's laboratory. While at UCSF, Golde met several influential scientists who first sparked his interest in hormones.

In 1974, Golde left UCSF for the University of California, Los Angeles [UCLA], where he continues his affiliation today as Professor of Medicine, Emeritus. Throughout most of the 1970s, Golde's major field of research was in colony-stimulating factors. Golde observed cell lines to determine which tissues make colony-stimulating factors. In his laboratory at UCLA, Golde developed a major cell line called KG-1 with H. Phillip Koeffler. The KG-1 cell line was later used to clone alpha interferon. Golde began studying hairy-cell leukemia, researching the cell origins for the disease. Studying cultures of the Mo cell line (named after John Moore, a hairy-cell leukemia patient), Golde's laboratory was the first to purify human GM-CSF [granulocyte-macrophage colony-stimulating factor]. With Robert Gallo he discovered a specific strain of retrovirus named HTLV-II, and with his postdoc, Irvin Chen, was the first to clone the HTLV-II virus. Golde concludes the interview with a discussion of the relationship between the biotechnology and the pharmaceutical industries, issues regarding federal transfer of information, and thoughts on his contributions to medicine.

Interviewee
Interviewer
Place of interview
Format
Original file type MP3, PDF
Genre
Extent
  • 22 pages
Language
Subject
Rights Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
Rights holder
  • Science History Institute
Related URL
Credit line
  • Courtesy of Science History Institute

Physical location

Department
Collection

Interviewee biographical information

Born
  • October 23, 1940
  • New York, New York, United States
Died
  • August 09, 2004
  • New York, New York, United States

Education

Year Institution Degree Discipline
1962 Fairleigh Dickinson University BS Chemistry
1966 McGill University MD

Professional Experience

University of California, San Francisco. School of Medicine

  • 1972 to 1973 Instructor in Medicine
  • 1973 to 1974 Assistant Professor in Medicine

University of California, Los Angeles. School of Medicine

  • 1974 to 1975 Assistant Professor of Medicine
  • 1975 to 1979 Associate Professor of Medicine
  • 1979 to 1991 Professor of Medicine
  • 1991 Professor of Medicine Emeritus

Cornell University

  • 1991 Professor of Medicine, Medical College
  • 1992 Professor of Molecular Pharmacology and Therapeutics, Graduate School of Medical Sciences

Memorial Sloan-Kettering Cancer Center

  • 1991 Member
  • 1991 to 1996 Head, Division of Hematologic Oncology
  • 1996 Physician-in-Chief, Memorial Hospital

Honors

Year(s) Award
1962 to 1966 University Scholar, McGill University
1965 Alpha Omega Alpha Honor Society, McGill University
1966 J. Francis Williams Prize in Medicine, McGill University
1986 Outstanding Faculty Research Lecturer, UCLA
1986 MERIT Award, National Institutes of Health
1991 Enid A. Haupt Professor of Hematologic Oncology, Memorial Sloan-Kettering Cancer Center

Cite as

David W. Golde, interviewed by Audra J. Wolfe in New York, New York on December 15, 1999. Philadelphia: Science History Institute, n.d. Oral History Transcript 0189. https://digital.sciencehistory.org/works/ff365621b.

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PDF — 173 KB
golde_dw_0189_FULL.pdf

The published version of the transcript may diverge from the interview audio due to edits to the transcript made by staff of the Center for Oral History, often at the request of the interviewee, during the transcript review process.

Complete Interview Audio File Web-quality download

2 Separate Interview Segments Archival-quality downloads